Studies of the elemental composition of wild raw materials are relevant and significant due to the high efficiency and biological availability of organometallic forms contained in plants. The purpose of the study is to study the macro- and microelement composition of motherwort herb five-lobed natural phytocenosis of the Voronezh region. Raw materials were harvested during the flowering of the plant in the Voronezh State Natural Biosphere Reserve. The microelement composition of the samples was studied mass spectroscopically on an ELAN-DRC instrument. It was revealed that the content of the microelement complex is 5.8%, 59 elements were determined. Macroelements make up 96.31% of the total elemental composition of the five-lobed hollow grass. The macroelements are based on potassium (more than 30 mg/g), as well as calcium (more than 16 mg/g). Essential trace elements make up 3.08% of the total mineral complex of the five-lobed hollow grass. Among them, the highest content was noted for silicon (more than 1.4 mg/g), iron (more than 0.1 mg/g). The content of regulated heavy metals and arsenic in the grass of the five-bladed dummy complies with the requirements of regulatory documentation. Lead, mercury, cadmium and arsenic account for 0.0008% of the total mineral complex of raw materials. The share of toxic and little-studied elements in the total mineral complex of the grass of the five-lobed dummy is 0.61%. The highest content was observed for aluminum (191.4 μg/g), strontium (65.2 μg/g), barium (70.3 μg/g), titanium (19.2 μg/g), rubidium (5.68 μg/g). The high ability of the five-lobed puberty grass to accumulate phosphorus, potassium, copper, zinc, cadmium from the soil, as well as a significant opportunity to accumulate calcium, magnesium, molybdenum, nickel, strontium and tellurium, is shown.